Endocrine Abstracts

Polycystic ovary syndrome (PCOS) is a common hormonal, metabolic and reproductive disorder characterized by androgen excess, ovulatory dysfunction and polycystic ovaries. The phenotypic presentation might differ between referral and unselected populations and varies within an individual over time and between individuals of different ethnic and geographic regions. Women with PCOS have increased prevalence of prediabetes and diabetes and have multiple risk factors for cardiometa...

Obesity and type 2 diabetes are common and complex traits that are closely related and the term ‘diabesity’ is being used for the twin global epidemic of these two disorders. PCOS is another common and complex disorder characterized by androgen excess, oligo-anovulation and polycystic ovaries on ultrasound. PCOS is linked with both obesity and type 2 diabetes. Although obesity and type 2 diabetes are not universally observed in PCOS, many women with PCOS are obese an...

Hirsutism, defined as excessive male-pattern terminal hair growth in females, affects about 5–10% of the women of reproductive age depending on the population studied and the method used to determine its presence. Hirsutism is the primary clinical diagnostic criterion of hyperandrogenism. Hyperandrogenism can result from increased androgen production and/or increased sensitivity of hair follicles to androgens. The presence of hirsutism in women can lead to significant psy...

Background: The symptoms typically associated with polycystic ovary syndrome (PCOS) such as acne, hirsutism, irregular menses, amenorrhoea, obesity and infertility are a major source of psychological morbidity and can negatively affect quality of life (QOL). Limited data are available regarding effects of different treatment modalities on emotional distress of women with PCOS.Objective: To determine potential impact of treatment on health-related quality...

Introduction: Increased adrenocortical production appears to be associated with acne and hirsutism in PCOS. However, the etiological role of androgens in the pathogenesis of acne per se is far from being clear. In the present study, we aimed to evaluate adrenocortical function in women with post-adolescent severe acne in comparison with patients with PCOS and healthy women.Design: The study included 32 women with post-adolescent severe acne, 32 ...

Background: Periodontal disease (diseases of the tissues around teeth) and polycystic ovary syndrome (PCOS) are common disorders in women with a significant public health impact. Both disorders appear to be associated with diabetes and cardiometabolic risk. There are no published data regarding periodontal disease in PCOS.Objective: To determine periodontal status in women with PCOS compared to healthy women.Methods: We studied 25 ...